Missouri is Global Leader for ECHO Show-Me ECHO (Extension for Community Healthcare Outcomes) uses videoconferencing to connect interdisciplinary teams of experts with primary care providers and other professionals. They collaborate in interactive case-based learning to develop advanced skills and best practices, which improves patient care access, quality and efficiency. Show-Me ECHO learning sessions also offer free continuing education and are provided at no cost to participating sites and individuals. Show-Me ECHO is a state-funded telehealth project operated by the Missouri Telehealth Network at the University of Missouri School of Medicine. MU’s ECHO program launched in 2014 and was created using a process developed by the University of New Mexico to educate and train participating providers in specific disease states or conditions. Today, New Mexico’s founding ECHO program has designated MU’s Show-Me ECHO as one of 14 global Suberhubs for training others to create ECHOs. MU has also launched some of the first and only ECHOs in such areas as COVID-19, opioid use, rural veterans behavioral health, developmental disabilities and kidney disease. New Show-Me ECHOs are continuously addressing pressing health needs. For details on how to launch your own ECHO or for questions about the trainings, contact Lindsey Beckmann, associate director, at 573-884-3753 or firstname.lastname@example.org.